Hair growth is in your DNA

SULT1A1

(Sulfotransferase 1A1): This gene helps predict how well your body activates minoxidil, a key ingredient for hair growth. Variants may indicate whether you need a higher dose or special additives like tretinoin for best results.

SRD5A1 & SRD5A2

Steroid 5-Alpha-Reductase: These genes affect how much DHT (a hormone linked to hair loss) your body produces. High activity can increase hair loss risk, suggesting the use of DHT-blocking treatments and selecting between finasteride, dutasteride, or spironolactone, which works as an anti-androgen to block DHT. Additionally, melatonin can act as an anti-androgen and may be used to enhance the effects of these treatments.

MTHFR

Methylenetetrahydrofolate Reductase: This gene influences your body’s folate levels, which are essential for healthy cell growth, including hair follicles. Variants may impact your need for folate supplements.

ACE

Angiotensin-Converting Enzyme: ACE affects blood flow. Variants here may determine how well circulation-boosting treatments, like minoxidil or caffeine, work to enhance hair growth.

GPR44-1 & GPR44-2

Prostaglandin D2 Receptor: These genes help us understand your sensitivity to prostaglandin D2, a compound that can cause hair loss. Cetirizine, a prostaglandin D2 inhibitor, may be effective for managing hair loss by blocking this pathway.

PTGFR-1, 2, 3

Prostaglandin F Receptor: These genes impact how well your body responds to latanoprost, a treatment that promotes hair growth through prostaglandin pathways. Variants in these genes can indicate whether latanoprost will be effective for you.

COL1A1

Collagen Type 1 Alpha 1: This gene affects collagen production, which supports hair structure. Variants can influence your hair’s strength and resilience, and whether collagen supplements may help.

PTGES2

Prostaglandin E Synthase 2: This gene plays a role in producing prostaglandins that help hair growth. Variants can indicate how effective treatments like minoxidil might be for you.

NQO1

NAD(P)H Quinone Dehydrogenase 1: This gene is related to your body’s antioxidant defenses. Low activity may mean oxidative stress is contributing to hair loss, suggesting antioxidant treatments.

BTD

BTD (Biotinidase): This gene helps your body use biotin, an important vitamin for hair growth. Variants may reveal whether you need extra biotin to support healthy hair.

CYP19A1

Aromatase: This gene controls how much testosterone is converted to estrogen. Low activity may lead to higher DHT levels, which could accelerate hair loss, guiding the use of anti-androgens like spironolactone, 17-α estradiol, or melatonin, which can help reduce DHT production and enhance hair growth effects.

SLC23A1

Vitamin C Transporter: This gene controls how well your body absorbs vitamin C, which is essential for hair strength and health. Variants may suggest a need for supplementation.

GR-alpha

Glucocorticoid Receptor Alpha: This gene affects how your body responds to corticosteroids, which can reduce inflammation that might harm hair follicles.

CRABP2

Cellular Retinoic Acid Binding Protein 2: This gene is involved in how your body uses vitamin A, which supports a healthy scalp and hair. Variants may suggest vitamin A supplementation like Tretinoin.

ZPR1

Zinc Finger Protein ZPR1: This gene is linked to zinc levels, and variants might suggest the need for zinc supplements, which are important for hair health.

DMGDH

Dimethylglycine Dehydrogenase: This gene affects your body’s selenium levels. Low selenium can impact hair health, so variants here might suggest the need for supplementation.

MUC1

Mucin 1: This gene is related to magnesium absorption. Variants could indicate if magnesium supplementation might benefit your hair health.